Hyperemesis gravidarum (HG) is seldom fully understood, despite affecting approximately 3% of pregnancies in the U.S. each year, leading to more than 160,000 emergency room visits. Commonly mislabeled as severe morning sickness, HG manifests as debilitating nausea and vomiting that can strike mothers-to-be persistently, making it impossible for many to maintain their usual daily activities.